What is Tretizen Soft Capsule?
This capsule contains Isotretinoin as its active drug. Isotretinoin or 13 cis retinoic acid is an orally administered retinoid. It is mainly used for cases of severe acne that are showing no response when treated with other medications or therapies. Nodular acne and cystic acne are the commonly occurring forms of severe acne.
They cause big, deep, and painful cysts or nodules on the skin. These forms of acne can occur independently or both symptoms may be present together. This condition is known as nodulocystic acne. Severe acne is quite difficult to treat. It can cause scarring if it is left untreated.
How Does Tretizen Soft Capsule Treat Acne?
Isotretinoin reduces the oil secreted by the pores present in the skin. Isotretinoin does not have any antimicrobial action of its own. However, since the oil production is decreased, this will prevent the development of clogged pores and prevent the colonization of the sebum and the pores by bacteria. It also reduces the appearance of papules and pustules which develop on the skin.
Isotretinoin is also known to change the characteristics of the sebum secreted by the skin. It also prevents the skin from hardening abnormally.
Directions for Use
Tretizen Soft Capsule is supposed to be taken orally. The capsule is to be swallowed whole with a glass of water. Do not puncture or try to chew it. It is generally recommended to take it with food. This helps to increase the absorption of the drug Isotretinoin into the bloodstream. However, some formulations can be taken both with or without food.
How Long Does It Take for a Tretizen Soft Capsule to Work?
A 20-week course of 0.5 to one milligram per kg daily brings about remission in most cases of cystic acne.
Further, it also depends on how regularly you have been taking your medication. It also depends on the intensity of the presenting symptoms of your acne.
What are the Dosage Instructions for Tretizen?
Tretizen is usually taken two times a day for around 15 to 20 weeks. Your dosages are decided according to what works the best for you according to your age, severity of the presenting symptoms, response to the therapy.
Make sure that you do not stop taking the medicine even if you start feeling better. Interrupting the therapy sooner than recommended makes your symptoms come back or even worse in them.
The usual adult dose of Isotretinoin for severe recalcitrant nodular acne is around 0.5 mg to 1 mg per kg of body weight per day orally. It is taken in 2 divided doses. Increased dosage upto 2 mg/kg per day may be needed for severe acne vulgaris with scarring or severe nodular acne on the trunk.
If the symptoms come back even after completing the full treatment then they can be treated similarly. Relapse in symptoms is however not so common.
Overdosing symptoms include headache, nausea, abdominal discomfort. In case you develop these symptoms contact your doctor immediately.
In case you skip a dose, take the next dose as soon as you remember it. However, if the time for the next door is already near then forget about the dose that you missed and start following the original routine.
Do not double the dose or overdose the medicine to make up for the dose that has been missed by you as it will make it harder and better and it may lead to the development of harmful symptoms that occur due to overdosing.
Sub Products of Tretizen
Tretizen 10 mg Soft Capsule
It is recommended to start your treatment with a lower dose of Tretizen. This is because suddenly taking a bigger dose may lead to the development of harmful symptoms. Starting with a lower dose allows your body to adapt to the drug.
Tretizen 20 mg Capsule
It is the greater dose of isotretinoin. The dosage will be gradually increased by the doctor only not doing this on. It is also mostly given in cases that are really very severe.
Mechanism of Action
The drug Isotretinoin primarily reduces the production of sebum. Its effect of reducing the skin bacteria is secondary. corrects abnormal keratinization of follicles and causes a dramatic improvement in skin quality and in your symptoms of acne. It is also not accumulated in the body like other retinoids.
Adverse Side Effects
There is frequent dryness of the skin.
Cheilitis occurs in some patients
Thinning of hair may occur.
The eyes, nose, and mouth also experience dryness.
Epistaxis is also a commonly reported side effect.
Some patients may develop conjunctivitis.
Bleeding may occur from the nose.
Crusting of skin may occur.
Bloody Stools may develop after initial episodes of abdominal pain.
It reduces bone density, therefore it is advisable to avoid any physical activity which may accidentally lead to fractures.
It can lead to an increase in the Heart Rate.
Flu-like symptoms develop in some patients.
It has been found that isotretinoin also leads to rising in serum lipids.
Warnings and Precautions
It is contraindicated in women who are likely to become pregnant during the therapy or up to one month after the therapy is completed.
Inform your consulting medical health personnel if your side effects do not go away even if you have been taking the medicine for quite some time now.
Discontinue the use if you develop any adverse symptoms like changes in vision, ringing in the ears, swelling in the chest, and pain.
To relieve the dryness in the mouth, drink plenty of water and use moisturizers.
Wear sunscreen if you go out insane. You can wear any other protective covering to prevent the affected apart from being exposed to the sun.
If your symptoms of stomach pain and nausea are particularly severe inform your doctor right away as it may indicate the development of pancreatitis and this may sometimes be fatal.
Tell your doctor right away if you have any serious psychological side effects like mental changes, mood swings, development of depression, anxiety, thoughts of suicide, and self-harm.
Do not ignore the development of Tingling feeling in the skin, back/joint/muscle pain.
Signs of infection like fever and persistent sore throat should also not be ignored.
Tell your doctor if you experience painful swallowing.
Also, stop taking this medicine if you develop painful peeling of skin on your palms and soles.
Doctor if you have a family history of diabetes or high blood fat levels.
Who Should Not Take It?
Women who are pregnant or are planning to become pregnant during the course of the treatment should not speak this medicine.
Patients who are allergic to any of the contents of Tretizen Soft Capsule should avoid taking this medicine. Symptoms of an allergic reaction include rashes, dizzy feeling, difficulty in breathing.
This medicine should be used in children with caution as children are more sensitive to some of the side effects like bone and muscle pain.
Patients who have sunburned skin should also avoid using risk medicine.
Why Buy Tretizen Soft Capsule at Medicationplace.com?
100% Good Quality Guarantee
Our products are FDA approved. Our quality of products is guaranteed and it is regulated by repeated investigations.
100% Secure Payment Methods
You do not have to fear the safety of your details or fraud. Our transactions are totally secured.
Is it safe to use a Tretizen capsule during pregnancy?
No, it is not safe to take Tretizen during pregnancy. Isotretinoin is a highly teratogenic drug. Up to 25% of the fetuses who have been exposed to it have had birth defects. The defects can be as serious as craniofacial abnormalities, heart abnormalities, and central nervous system abnormality.
Is it safe to use Tretizen while breastfeeding?
Isotretinoin is not known to be passed to breast milk however similar drugs can pass through breast milk. So, it is advisable that breastfeeding women should not take this medicine.
Is it safe to use Tretizen by patients with liver disorders?
New, it is not safe to be used by patients with liver diseases. It may work on your problems further.
Is it safe to drive after taking Tretizen?
Do not drive after taking this medicine especially after dark as it may affect your vision. Also do not operate any heavy machinery after taking isotretinoin.
Can I take alcohol while taking this medicine?
No, do not take alcohol along with isotretinoin as it may increase the chances of developing problems like pancreatitis.
Tretizen Soft Capsule Alternatives
Isotretinoin is a retinoid that is very commonly used to treat severe acne. About as much as 85% of the patients who have taken Isotretinoin therapy have reported improvement in their symptoms after completing the treatment.
Isotretinoin is also sometimes used in the prevention and treatment of skin cancers. Conditions like oral leukoplakia, actinic keratosis, and other premalignant lesions can also be treated. However, the benefit and risk ratio for the treatment of these other diseases is not clear.
This medication is easily available from any nearby pharmacy after taking the doctor’s prescription full time.