What is Isotroin 5 Mg Soft Capsule?
Isotroin 5 mg contains isotretinoin which falls under the category of Systemic Therapy for acne vulgaris. Acne is the most common skin disease in adolescent boys and girls. Under androgenic stimulation, the sebaceous follicle of the face and neck produces excess sebum and gets colonized by bacteria and yeast.
Isotretinoin is also effective in the prevention as well as treatment of skin cancer. Oral leukoplakia, actinic keratosis, and other premalignant lesions can be treated, but the benefit-risk ratio is not clear.
Systemic therapy includes antibiotics and isotretinoin.
How Does Isotroin 5 Mg Soft Capsule Treat Severe Acne?
Severe nodular acne or acne vulgaris is the formation of red, swollen, tender lumps in the skin. While the exact way in which it works is not known yet. It has been observed that isotretinoin inhibits sebaceous gland function and keratinization when administered at pharmacologic doses.
It has been seen that the drug reduces the sebaceous gland size and sebum production as well. It also reduces the oil that is produced in the skin naturally. The half-life of isotretinoin is around 18 hours. It is not accumulated in the body like other retinoids.
Directions for Use
Take this medicine as directed by your doctor. It can be taken with food, however, it is not compulsory. Swallow the medicine whole with water. Do not chew, crush or suck the medicine. Take the dose as recommended by the medical professional personnel only.
How Long Does It Take For Isotroin 5 Mg Soft Capsule to Work?
Isotroin treatment starts showing results within a week to 10 days. A twenty-week course of 0.5-1 milligram per kg daily brings about her mission in most cases of cysts of acne. After variable intervals, relapses may occur but they can be treated in a similar fashion. A 3-month course is generally recommended.
What are the Dosage Instructions for Isotroin 5 Mg Soft Capsule?
Isotroin therapies are started at a dose as low as 5 milligrams per kilogram per day. This continued for four weeks. After that, the dosage is increased as per the tolerance level of the patient. The dosages increased until a total dose of 120 to 150 mg per kg was reached.
Dosage varies from person to person according to the severity of acne and according to their health conditions. It should be taken strictly according to the dosage recommended by the doctor. Some patients experience Acne remission only after taking oral therapy. Some patients require additional therapies.
Headache, dizziness, vomiting, stomach pain, warmth or tingling sensation in the face, swollen and cracked lips, and loss of balance or coordination are the common symptoms of overdose of Isotroin. Isotroin overdose can also be caused by taking a vitamin A supplement. In case of overdose contact the medical health personnel immediately. Try to seek help at the poison helpline.
In case you miss the dose of isotretinoin, take the dose as soon as you remember it. Do not take the dose if the time for the other doors has approached. Leave that missed dose and go back to your normal dosing schedule. Taking double doses to compensate for the missed dose can lead to overdosing and it can cause associated adverse symptoms.
Sub Products of Isotroin 5 Mg Soft Capsule
Isotroin 5 Milligrams
Isotroin 10 Milligrams
Isotroin 20 Milligrams
Mechanism of Action
Isotretinoin is also called 13-cis retinoic acid. It is an orally administered retinoid that reduces the production of sebum. It also corrects abnormal keratinization of follicles and therefore, it causes dramatic improvement.
This causes a secondary decrease in skin bacteria. This helps to get relief from redness and soreness. Bacterial lipase produces fatty acids from sebum.
These fatty acids irritate the follicular ducts which lead to retention of secretions and hyperkeratosis. These are also known as comedones. These comedones are formed which make a rupture into the dermis causing inflammation and pustulation.
Adverse Side Effects
It has frequent side effects like cheilitis.
It causes dryness of skin, eyes, nose, and mouth. It can also lead to nosebleeds and eczema.
It can cause Mental health problems like depression or psychosis.
It can lead to inflammation of the liver, pancreas, or intestine in severe cases.
Bone and muscle changes can also occur.
It can also cause some severe allergic reactions.
It may also cause epistaxis.
It can cause Hepatotoxicity.
It may lead to pancreatitis.
It can lead to pruritus.
Conjunctivitis is also a frequent side effect.
It can cause paronychia.
Isotretinoin may lead to rising in serum lipids and intracranial tension.
It can lead to hearing and vision defects.
It can also cause musculoskeletal symptoms due to an increase in serum lipids.
It can increase problems related to blood sugar levels.
Warnings and Precautions
Isotretinoin is highly teratogenic. Up to 25% of exposed fetuses had birth defects, like craniofacial, heart, and central nervous system abnormalities.
This is collectively known as Accutane embryopathy.
It can also cause abnormalities of the face, ears, eyes, and nose in the skull. It can cause parathyroid problems in fetuses.
It can cause other defects like cleft palate in fetuses.
It can lead to low IQ in newborn babies.
It is prohibited for women who are likely to be pregnant recently.
Isotretinoin should not be used for a long time if it’s unresponsive.
Isotroin should be used under the guidance of a dermatologist only.
Do not donate blood while taking Isotroin treatment and up to after one month of the therapy.
To deal with side effects apply a moisturizer after taking a bath. Use a moisturizer for your lips. Do not use harsh and drying soaps to shower as it may worsen the symptoms of dryness.
Who Should Not Take It?
You should not take Isotroin if you are pregnant or are trying to get pregnant in the next month.
Do not take Isotroin if you are breastfeeding.
Isotroin should be used in adolescent patients that are after the age of 12 during puberty only.
Patients who are allergic to isotretinoin should not take it.
Patients with kidney disorders should use it with extreme caution.
Patients with liver disorders should only use Isotroin after consultation with their doctor.
Patients with heart diseases are not recommended to use Isotroin.
Patients with hypervitaminosis A should not take Isotroin. hypervitaminosis A is an increased level of vitamin A in the body.
Patients with anorexia or patients who eat too little are not recommended to use Isotroin 5 mg.
For patients with mental health problems like depression, move changes, aggressive behavior is not recommended to use Isotroin.
Asthma patients should not use Isotroin.
Isotroin makes you more prone to sunburn. Therefore, avoid tanning and sunbathing.
For up to six months after completion of the Isotroin, therapy avoids skin waxing, laser treatments, or Dermabrasion as it may lead to scarring.
Patients with low tolerance to isotretinoin dosages should abstain from taking these medicines.
Do not use Isotroin if you use contact lenses.
Patients with diabetes mellitus should not use Isotroin.
Patients suffering from high levels of cholesterol and triglyceride levels should not use Isotroin.
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Is it safe to use Isotroin 5 mg?
Isotroin is a closely monitored medication so you will need to arrange frequent checkups with your doctor. Inform your doctor about all your conditions and he will manage the dosage.
Along with what other medicines should you not take isotretinoin?
Isotroin should be used with extreme caution if you are taking Tetracyclines antibiotics, birth control pills (Progesterone only pills), Vitamin A supplements, Medicines to cure epilepsy called medicines to cure mental health problems, or with corticosteroid medicines.
Can I consume alcohol while taking isotretinoin?
It is recommended that you do not consume alcohol when taking Isotroin 5 mg.
Can I drive after taking Isotroin 5mg?
Isotretinoin may cause drowsiness, dizziness, and eye problems. Therefore it is advisable that you do not drive after taking this medicine. Do not operate heavy machinery either.
Topical steroids like beclomethasone
Topical antibiotics like erythromycin
Some cases of acne vulgaris, if left untreated, may leave scars. Only such extreme unresponsive cases are to be treated with Isotroin. Store it at 20 degrees Celsius to 25 degrees Celsius. Don’t let the children or pets reach out for the medicine.