About Isotroin 20 Mg Soft Capsule
This is a method of systemic therapy to treat acne vulgaris the other systemic treatment method includes antibiotics. Systemic use of drugs in acne is indicated only in severe cases with cysts and pustules which are likely to form scars if left unattended. Severe nodular acne or acne vulgaris is the formation of red, swollen, and tender lumps in the skin.
While the exact way in which it works is not known yet, it has been observed that Isotroin inhibits sebaceous gland function and keratinization when it is administered at pharmacological doses. It has been seen that it reduces the sebaceous gland size and sebum production as well. The natural production of oil in the skin is also reduced. Isotroin is not accumulated in the body like other retinoids and it has a half-life of around 18 hours.
Isotroin 20 Mg Soft Capsule Composition
It contains a drug called isotretinoin which falls under the category of systemic therapy drugs for acne vulgaris. Acne is the most common skin disease in adolescent boys and girls. Under the antigenic stimulation, the sebaceous follicle of the face and neck produces excess sebum which gets colonized by bacteria and yeast.
Manufacturer of Isotroin 20 Mg Soft Capsule
Isotroin 20 Mg is manufactured by an Indian multinational pharmaceutical company Cipla limited. It is headquartered in Mumbai, India. It was founded in 1935. They strive to provide the most advanced medicines manufactured with the best of resources to everyone all across the globe.
Uses of Isotroin 20 Mg Soft Capsule
Isotretinoin is sometimes used in the prevention and treatment of skin cancers.
Conditions like oral leukoplakia Can also be treated.
It can cause improvements in symptoms of Actinic keratosis.
Other premalignant lesions can also be treated.
It prevents the skin from hardening abnormally.
It is primarily used to treat severe cases of acne which have not responded to any other methods of treatment.
How Does Isotroin 20 Mg Soft Capsule Work?
The drug isotretinoin is also called 13 cis retinoic acids. It is an orally administered retinoid and it reduces the production of sebum. It also corrects abnormal keratinization of follicles and therefore it causes a great improvement in skin quality. It also causes a secondary decrease in the bacteria that colonize the skin. It helps to get a huge relief from redness and soreness in the skin.
What happens is that bacteria lipase produces fatty acids from sebum and these fatty acids irritate the follicular ducts finally leading to retention of secretions and a condition called hyperkeratosis. These are also known as comedones. These comedones are formed and may rupture into the dermis causing inflammation and pustulation.
How to Take Isotroin 20 Mg Soft Capsule?
Take it according to the dosage schedule prescribed by your consulting doctor. Isotroin 20 Mg Soft Capsule is supposed to be taken orally and the patient should swallow it whole along with water. Do not puncture or try to chew the capsule.
It is mostly recommended to take it with food however some formulations can be taken both with or without food. Taking it with food helps to increase the absorption of the drug isotretinoin into the bloodstream.
Isotroin therapies are started at a very low dose of about 5 milligrams per kilogram per day. Thus it is visible that Isotroin 20 Mg is a pretty Higher dose. It is introduced after continuing the lower doses for about 4 weeks and after gradually increasing the tolerance level of the patient. The dosage varies from person to person according to the severity of the acne and according to their health conditions, age, and response to the treatment.
The medication should be taken strictly according to the dosage recommended by your medical health personnel. In case of overdose the symptoms experienced are headache dizziness, nausea vomiting, stomach pain, warmth or tingling sensation in the face, swollen and cracked lips, and loss of balance and coordination. Isotroin overdose can also be caused by taking a vitamin A supplement. In case of overdose, contact the medical health emergency immediately.
What If a Dose is Skipped?
In case you miss a dose of isotretinoin, take the dose as soon as you remember about it. Do not take the dose if the time for the other one has already approached. Leave the dose that you missed and go back to following your normal dosing schedule.
Taking a double dose or overdosing the medicine to compensate for what you have missed can lead to overdosing and it can cause associated adverse symptoms.
Side Effects of Isotroin 20 Mg Soft Capsule
It can cause cheilitis.
It can cause some mental health problems like depression, anxiety disorder, and psychosis.
It can lead to the inflammation of the liver, pancreas, or intestine in severe cases.
Some bone and muscle changes are also reported.
It may also cause epistaxis.
In some cases, a fatal condition known as pancreatitis can develop.
Isotretinoin may lead to an increase in serum lipids and intracranial tension.
It can also cause some hearing and vision problems.
It can cause dryness of skin, eyes, nose, and mouth.
It can lead to nosebleeds and eczema.
It can lead to Pruritus.
Conjunctivitis is also a frequently reported side effect.
It can cause paronychia.
It can make you more prone to sunbirds. Therefore the patient must avoid tanning and sunbathing.
Drug Interactions of Isotroin 20 Mg Soft Capsule
Isotretinoin may react negatively to the following medicines and drugs.
Adderall containing amphetamine and dextroamphetamine
Adderall XR containing amphetamine and dextroamphetamine
Fish Oil (omega-3 polyunsaturated fatty acids)
Lithium Carbonate ER (lithium)
Probiotic Formula which contains Bifidobacterium infantis or lactobacillus acidophilus
Prozac which contains fluoxetine
Vitamin B12 (cyanocobalamin)
Isotretinoin is a teratogenic drug therefore women who are pregnant or are planning to be Pregnant in the upcoming month should not take this medicine. It can cause birth defects like craniofacial abnormalities, heart, and central nervous system abnormalities. It can cause parathyroid problems in fetuses and other defects like cleft palate and low IQ in newborn babies.
It should be used under the guidance of a dermatologist only.
Do not donate blood while taking Isotroin and up to one month after the treatment.
The side effects related to the drying of the skin can be reduced by using moisturizers and by drinking plenty of water.
Do not use harsh soaps, do not get in skin treatment like waxing or any other abrasive treatment done.
Breastfeeding women should also not use this.
Isotroin should be used only in patients above the age of 12.
Patients with kidney disorders should use it only after consulting it with their doctor.
Patients with liver disorders and heart diseases should not use this medication.
Patients with hypervitaminosis should not take Isotroin.
Patients with anorexia should also avoid it.
How to Store?
You should store it in a cool and dry place, an area away from direct heat and too much humidity. Store it below a temperature of 30 degrees Celsius and do not let it land in front of your children or in front of your pets.
Isotroin 20 Mg Soft Capsule Review
Thus, Isotroin is a good drug of choice to treat severe acne which has shown no response to any other method of treatment.