What is Imiquad Sachet?
Imiquad sachet is used for the treatment of a condition called actinic keratosis. It contains drug imiquimod in a definite concentration. Imiquimod is an Imidazoquinoline Derivative and it is an immune response modifier.
Actinic keratosis is a condition in which a rough and scaly, crusted patch develops on the skin, and this results from years of sun exposure. This is why it is also called solar keratosis. Chronic exposure to ultraviolet rays from the sun causes it to become a very common pre-cancer which can develop into squamous cell skin cancer.
The pre-cancer lesions are not life-threatening and can be prevented from developing into full-blown cancer. This condition mostly affects older aged people. To prevent the situation from developing further, reduce sun exposure.
It is commonly found on the face, the ears, lips, forearms, back of hands, neck, and scalp. A lesion may take years to develop but it is still removed as a precaution as it can become cancerous. A patch of actinic keratosis enlarges very slowly and may even take upto years to develop.
It is also used for the treatment of other Dermatological disorders like genital warts which present as small bumps on the skin which can develop around the genital area or even around the anal area.
Glenmark pharmaceuticals limited is the company that manufactures this medicinal preparation. It was established in 1977. It is set up in Mumbai, India.
How Does Imiquad Sachet Treat Actinic Keratosis?
Medicinal preparation activates the immune system to release cytokines which help in defending the body against the viruses that are responsible for causing the development of this condition and prevents it from developing into basal cancer. It helps in controlling, preventing, and improving the condition of your actinic keratosis and promotes the formation and development of a new layer of healthy skin.
Directions of Use
The first step, which is often ignored, is to wash your hands properly before you apply the solution. This prevents any bacteria on your hand from landing on your wound. The next step is to clean the surface of the skin where you are going to apply the solution of imiquimod.
After that, use a gauze or cotton swab, or any other applicator and apply a liberal amount of the solution. Use a new applicator for each use. Application of a thin layer is enough. Also, ask your consulting medical health personal for any other important directions regarding the proper application of the medicine.
Imiquimod is mainly for tropical applications. In case it is applied in the inner lip area or inside the mouth or the nose by mistake, rinse the area immediately. Do not apply imiquimod to scraped skin or damaged skin.
Avoid getting the solution in your eyes. Wash your hands after you apply the solution so that this can be avoided. If you get the solution in your eyes by mistake, wash your eyes immediately with large volumes of water. Seek medical help immediately to prevent further damage to your eyes.
How Long Does it Take for an Imiquad Sachet to Work?
It may need around 8 to 10 weeks of application of this medicine for your symptoms to disappear completely however you may notice the effects of the medicine after using the medicine for about 4 weeks.
This can be identified by noticing flaking or formation of scabs on the area that is healing. However, do not stop using the medicine before completing the full course even if you notice a remission of symptoms as there may be a relapse and it will take even longer to cure the problem after this.
What are the Dosage Instructions for Imiquad Sachet?
Apply a small amount of the solution on the affected area or as directed by the medical health personnel. Apply a liberal amount of the imiquimod solution. A sachet meant for single-use is sufficient to cover a wart area of 20 square cm. A sachet should not be re-used after it has been opened.
Apply it twice every week. Do not change or alter the dosage schedule on your own. Strictly follow the schedule that has been given to you by your consulting doctor.
Your dose is decided by the severity of your presenting symptoms, age, and what works the best for you. Inform your doctor if you observe no improvement even after following the dosage routine properly. Bring any kind of side effects that you experience to the notice of your doctor so that they can be controlled.
Severe skin irritation, a feeling of light-headedness, or fainting may be experienced by patients in case of overdosing.
In case you miss a dosage, apply for this medicine as soon as you remember it. If the time for the second dose of the cream is near, miss the doors and start following the original routine. Do not overuse or overdose the solution to make a further dose that has been missed overdosing the solution may lead to symptoms associated with overdosing.
This may be harmful. Inform your doctor if symptoms like burning and itching develop. Overusing will not make the skin heal faster. Also, take care that you use it in the same amount every time.
Sub Products of Imiquad Sachet
- Imiquad cream 12.5mg
- Imiquad cream 5%
- Imiquad injection
Mechanism of Action
Imiquimod acts on the innate and the acquired immune responses in both direct and indirect ways. In Direct action, this medicine binds to toll-like receptors (TLR) 7 and TLR 8 of macrophages, monocytes, and dendritic cells and induces apoptosis. When it acts indirectly, imiquimod induces the release of immune-modulatory cytokines.
Its effectiveness is also improved by its action on Langerhans cells and stimulates its ability to present antigens and it also enhances its migration to the draining lymph nodes where it ultimately presents the antigens to the T cells. This activates the adaptive immune response of the body.
The direct effects of imiquimod on cutaneous malignancies include the Induction of apoptosis in tumor cell lines. Imiquimod activates the main causative agent of apoptosis which is the caspase family of proteases.
Adverse Side Effects
- Dry skin
- Application site reactions
- Edema or swelling
- Skin flakes
- Skin ulcer
- Induration is a condition in which hardening of normally soft tissue or organ occurs
Warnings and Precautions
- Avoid taking a shower and avoid going to a swimming pool while you still have the medicine on your body.
- Do not apply the skin on cuts, wounds or damaged skin, or skin that has not yet healed from surgery.
- Do not cover the area with bandages after applying the medicine stop
- Inform your doctor about all the medications that you are taking including the vitamin supplements and the herbal medications as they may cause contraindications.
- Also, tell the doctor about all the previous treatments or surgeries that you have had.
- Inform the doctor about all your pre-existing medical conditions.
- Avoid sexual contact for as long as the treatment lasts and until your warts completely disappear.
- Avoid going out in the sun without taking proper precautions if you are in the sun for prolonged durations wear a broad-spectrum sunscreen.
- It may aggravate inflammatory skin conditions.
Who Should Not Take It?
- Pregnant females should not use it.
- Children between the age of 2 to 12 years with viral infections should also avoid it
- Immunosuppressed patients or patients with pre-existing autoimmune diseases should avoid it
- In case you have fever, rashes, or are currently experiencing flu-like symptoms then avoid it.
- Patients of xeroderma pigmentosum
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Is it safe to use this preparation during pregnancy?
Although there are limited human studies, it is not recommended that you use this medication while you are pregnant.
Is this preparation safe for use by breastfeeding women?
This medicine is safe for use by breastfeeding women after getting a proper prescription from a doctor.
Is it safe to use this medication in patients suffering from liver or kidney disorders?
Although no significant interactions have been established, it is still advisable that you inform consulting medical health personnel about all your pre-existing conditions before taking this medicine.
Imiquad Sachet Alternatives
- Qmica 12.5mg Cream
- Nilwart cream
This medicine, Imiquimod, is positively reviewed by a lot of Patients who have experienced relief from their skin conditions. This medicine should be stored in a cool and dry place away from direct heat and sunlight.
Below a temperature of about 30 degrees Celsius and beyond the reach of children and pets as it can be harmful if it is accidentally ingested by them. This medicine can be availed only after getting a doctor’s prescription.